11/30/2022 0 Comments Zofran over the counterThe FDA had previously noted that ondansetron could increase the risk of developing QT interval prolongation. Zofran and the other 5-HT3 receptor antagonists work by preventing this serotonin from binding to 5-HT3 receptors. When a patient undergoes cancer treatment, radiation or chemotherapy drugs can cause specialized cells in the intestine to release serotonin. Serotonin is produced largely in the gastrointestinal tract. These receptors exist in both the central and peripheral nervous system, and when joined with a neurotransmitter called serotonin, they can cause nausea and vomiting. Zofran works differently.Īs the class name suggests, Zofran targets 5-HT3 receptors in the body. Bismuth subsalicylate works by coating the stomach lining. Antiemetic agents are any drugs that prevent vomiting or nausea including over-the-counter antihistamines (Benadryl, Dramamine) or bismuth subsalicylate (Pepto-Bismol, Kaopectate).Īntihistamines prevent vomiting and nausea from sickness by blocking the inner ear’s messages to the brain. Zofran and other 5-HT3 receptor antagonists are considered antiemetic agents. The medication comes in 4 and 8 mg soluble film doses that dissolve on the tongue without water. MonoSol Rx developed a closely related drug, Zuplenz, and first sold it in October 2010. #ZOFRAN OVER THE COUNTER PROFESSIONAL#Our writers are members of professional associations, including American Medical Writers Association, American Bar Association, The Alliance of Professional Health Advocates and International Society for Medical Publication Professionals. The information on has been medically and legally reviewed by more than 30 expert contributors, including doctors, pharmacists, lawyers, patient advocates and other health care professionals. This means the high-quality information we provide comes from credible sources, such as peer-reviewed medical journals and expert interviews. is HONCode (Health On the Net Foundation) certified. Our team includes experienced medical writers, award-winning journalists, researchers and certified medical and legal experts. We’ve also connected thousands of people injured by drugs and medical devices with top-ranked national law firms to take action against negligent corporations. has provided reliable, trusted information about medications, medical devices and general health since 2008.
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